Iron(II)‐Catalyzed Aerobic Biomimetic Oxidation of Amines using a Hybrid Hydroquinone/Cobalt Catalyst as Electron Transfer Mediator

Herein we report the first FeII-catalyzed aerobic biomimetic oxidation of amines. This reaction involves several electron transfer steps and is inspired by biological in respiratory chain. The from amine to molecular oxygen aided two coupled catalytic redox systems, which lower energy barrier improve selectivity reaction. An iron hydrogen complex was utilized as substrate-selective dehydrogenation catalyst along with a bifunctional hydroquinone/cobalt Schiff base hybrid mediator. Various primary secondary amines were oxidized air their corresponding aldimines or ketimines good excellent yield.